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КА Бион-М №1Progress in space exploration and use was achieved through, among other things, space biology and physiology research onboard manned and unmanned space vehicles. The investigations helped elucidate the fundamental mechanisms underlying the structure and function of living systems exposed to altered gravity and other spaceflight effects. The results have led to advancements in space biology, physiology and biotechnology and have been widely applied in the implementation of manned space missions, including their medical support.


This a second call for scientific proposals for participation in Bion-M2 biosatellite animal studies. Following request of its partners, Institute for biomedical problems has extended the deadline for submission of the proposals to March 31, 2017. Below you will find brief information about the program.

In 2022, the Federal Space Agency of Russia (Roscosmos) and the Russian Academy of Sciences plan to launch the second unmanned biosatellite of the Bion-M series. The Bion-M2 spacecraft will be launched to a 800-1000 km geocircular orbit for 30 days. Today the Institute of Biomedical Problems of the Russian Academy of Sciences (IMBP RAS), the lead center responsible for the research program implementation, has initiated the development of the program.

IMBP RAS has the pleasure of inviting you to take part in Bion-M2 animal studies and submit science proposals.

The goal of Bion-M2 animal studies will be to investigate systemic, cellular and molecular mechanisms underlying adaptation of mammals to the combined effects of microgravity, cosmic radiation and other spaceflight factors as well as their readaptation to the terrestrial environment upon return to Earth.

Bion-M2 experiments will be performed on space-flown C57BL/6 mice as well as ground controls, housed in flight habitats and exposed to the simulated flight environment, and vivarium controls.

The investigations will be focused on the central nervous and sensory systems, muscular and skeletal structures, cardiovascular and respiratory systems, water-salt metabolism regulation, immune system, cell biology and regeneration.

The investigations will be performed pre-flight, during animal exposure to the real or simulated flight, and after flight to identify spaceflight effects and their mechanisms as well as the time-course of readaptation. No experimental interventions will be performed in orbit. Biosamples will be collected:

  • To detect acute spaceflight effects 1) approximately 2-3 hours after landing at the landing site (optional) and 2) 14-17 hours after landing at IMBP in Moscow;
  • To investigate recovery and readaptation to Earth’s gravity: 3) 3 days and 4) 7 days after landing.

Science proposals of up to 10 pages should be submitted to IMBP RAS ( no later than March 31, 2017. Proposals should include a brief background, goals and objectives of the study, methods, minimum/maximum sample size needed, expected results, as well as a program of preflight verification of the experimental design.

The proposals will be reviewed by an ad hoc committee and scored with respect to the following parameters: compliance with the Bion-M2 objectives, novelty and justification, feasibility of implementing proposed experiments on Bion-M2.

Priority will be given to the experiments that can complement each other, thus allowing a comprehensive approach to the study of physiological systems at different levels; the experiments that aim at investigating mechanisms of animal readaptation to Earth’s gravity after an extended spaceflight, as well as to the experiments that will produce data compatible with Bion-M1 results ( to make possible their comparative analysis.

After initial selection the proposed experiments will be integrated into a science research program, which may require modification of the original proposals.

2016 Februaryновости

SSC RF Institute of bio-medical problems of RAS, being the leading institution of the project, starts to create the scientific program of investigations and invites interested institutions to take part in animal investigations.

2015 JulyNews

Roscosmos signed the contract with SRC Progress for manufacturing space apparatus for conduction biomedical experiments BION-M#2.

2015 FebruaryNews

Researchers from IBMP and University of Florida managed to find an answer for the question why cosmonauts’ long exposure to weightlessness sometimes causes vision disorders.

2014 NovemberNews

On November 18 2014, the Russian Academy of Sciences has begun work XV Conference on Space Biology and Aerospace Medicine with international participation.

2014 SeptemberNews

On September 26 2014 in ITAR-TASS News Agency a conference was held. Preliminary results of biological experiments, carried out on board of Foton-M No.4 SC, were announced.

2014 SeptemberNews

The ground control experiment in scales of the Foton-M No.4 research SC program was successfully finished.

2014 SeptemberNews

On September, 1 at 13:18 Moscow time Foton-M No.4 SC landed in designated position of Orenburg district.

2014 JulyNews

On July, 19 at 00:50 Moscow time carrier rocket Soyuz-2.1a with Foton-M No.4 SC was launched from cosmodrome Baikonur.

2014 JulyNews

In the night of July, 16 upload of scientific equipment and biological objects in the Foton-M No.4 SC was successfully finished.

2014 MayNews

Information Letter.
Launch of Foton-M No.4 research spacecraft is planned on summer 2014 from cosmodrome Baikonur, Kazakhstan.

2014 FebruaryNews

Information Letter.
XV Conference on Space Biology and Aerospace Medicine with international participation "BION-M1 PROJECT: Results and Forward Plans". 18-20 of November 2014, The Conference will be held on the Presidium of the Russian Academy of Sciences, Moscow, Russia.

2013 SeptemberNews

Мemorandum on the results of studies conducted in mice after a 30-day space mission BION-M № 1.

2013 МayNews

May 22 IBMP RAS hosted a conference following the flight of spacecraft "Bion-M» №1.

2013 МayNews

OMEGAHAB Post-Landing Report.

2013 МayNews

On 19th of May at 07.12 the Landing Module BION-M1 successfully touched down at Orenburg region.

2013 апрельNews

April 19, 14 hours, 00 minutes (msk) from Launch Complex 31 of Baikonur Cosmodrome conducted a successful launch of a space rocket "Soyuz-2.1a" ...

2013 FebruaryNews

On February 18, accompanied by the specialists of Samara "TsSKB "Progress", SV "Bion-M" and carrier-rocket "Soyuz-2.1b" were delivered to launch area Baikonur ...

2012 JuneNews

"Bion-M1" is scheduled to launch April 15 - 25, 2013.

2011 FebruaryNews

Bioengineering tests of animal habitats (MLZh-01-01) were performed from February 8, 2011 through March 14, 2011 at the habitat’s manufacturer - Biophyspribor (St.-Petersburg, Russia). The habitats will house mice and geckos in the space environment (microgravity) ...

2010 NovemberNews

Bioengineering tests of the Kontur-BM unit were performed from November 5, 2010 through December 3, 2010 at the Institute of Biomedical Problems, Russian Academy of Sciences ...

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